14^th International Conference on Nanomaterials and Nanotechnology March 30- 31, 2017 Madrid, Spain

Biography:

Amparo Luna received her Bachelor´s degree in Chemical Engineering, Instituto Tecnológico de Veracruz in 1996 and PhD degree in the Organic Chemistry Program in 2002 from the Universidad de Oviedo, Spain, under the supervision of Prof. Vicente Gotor and Dr. Covadonga Astorga. In 2003, she joined the research group of Prof. Roland Furstoss at Faculté des Sciences de Luminy (Lab. Associé au CNRS, in Marseille (France) as a  Post-doctoral fellow. In 2004, she moved to the research group of Prof. Benito Alcaide (UCM, Madrid) where, in 2006, she was appointed as Assistant Professor and in 2015 she assumed a position of Associate Professor. Her research interests are focused on beta-lactam and allene chemistry, and metal-catalyzed coupling reactions.

Abstract:

Allenes are a class of compounds with two cumulative carbon-carbon double bonds, which are versatile synthetic intermediates in organic synthesis. These substrates have allowed chemists to prepare a variety of compounds of chemical and biological interest. The abundance of nitrogen-containing heterocycles in biologically active  molecules has occasioned many efforts for their synthesis and functionalization. In particular, the oxacycles is important because they are present in a wide range of natural products. On the other hand, in the design of eco-friendly processes, catalysts and solvents play a key factor from both an economic and environmental point of view. In the development of new chemical processes the reactions conditions should fulfill specific criteria: i) renewable feedstocks, ii) low VOC emission, iii) low flammability and iv) functional group compatibility. In our continuing efforts on the construction of potentially bioactive heterocycles, we have developed a new catalytic process using metal nanoparticles because of; NPs tend to be more reactive than their particulate metal counterparts as a result of increasing surface area with decreasing particle size. Palladium nanoparticles are one of the most used and efficient catalyst in the formation of C-C bond and other chemical transformations such as carbon-hetero atom bond formation. Herein, we described the use, for the first time, of a novel ligand-free catalytic system for obtaining the cyclization of allenols towards the preparation of  dihydrofurans and carbazoles. The prepared nanomaterial (PdNPs) displayed good activity on the construction of potentially bioactive heterocycles in aqueous media, providing good to excellent yields. The recyclability of the nanocatalyst has also been established (up to four cycles) giving rise to good isolated yields in successive runs.

Biography:

Nadezhda Nebogatikova has her expertise in the area of graphene functionalization, graphene quantum dots, suspensions and inks for 2D-inkjet printing. She has found an approach to create different fluorinated graphene-based materials. Her investigations of graphene fluorination opened new pathways for improving graphene-based devices with a wide range of electronic and structural properties. She has 14 publications and worked at Rzhanov Institute of Semiconductor Physics SB RAS in Novosibirsk since 2010.

Abstract:

Graphene electronics needs new materials with tunable electronic properties due to a set of excellent electronic and structural graphene properties and the zero band-gap in its electronic structure. The traditional pathways to open the bandgap in graphene layers are nanolithography. Unfortunately, there is a dramatic decrease in carrier mobility due to chemically active dangling bonds near the formed edges. The stability of graphene-based nanostructures without edge atoms has been investigated recently. One can create such materials by embedding graphene islands into a stable matrix. Such approach was realized in our previous studies of graphene layers and suspensions fluorination. Another decision is to cut holes in neighboring graphene layers and to bond the chemically active atoms from different layers forming a closed structure of sp2-hybridized carbon atoms. We used high energy ions (26-167 MeV) to create perforated few-layer graphene films. Both scanning electron microscopy and atomic force microscopy both demonstrate nanosized holes (20-40 nm in diameter) formed by ions irradiation. The initial ions energy determines the amount of  electronic loss and the value of a sharp local temperature rise in the films. As a consequence, the type of the holes edge may be reconstructed in the range from the dangling bonds to connected edges. We observed the bandgap and electric active traps appearance, dependently on ions energy. We found the conditions for tuning the film electronic and structural properties. The formation of a continuous graphene surface between two perforated layers is very attractive as well as for nanoelectronic devices because of the band-gap appearance in its electronic band structure, opportunity to save the carrier mobility and capability to transmit high electric currents in contrast to nanostructured graphene and semiconducting graphene nanoribbons. Moreover, such nanostructures are promising for sensors and molecule filters.

Biography:

J Vidal-Gancedo is a Tenured Scientist at the Materials Science Institut of Barcelona, ICMAB-CSIC and Researcher at the Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Barcelona, Spain. He obtained a PhD in Chemistry from the University of Barcelona in 1993. Actually also he is Scientist In-Charge of the ICMAB Electron Paramagnetic Resonance Laboratory and President of The Spanish Electron Paramagnetic Resonance Group, GERPE. His research interest focuses on molecular functional materials based on organic radicals, molecular nanoscience, and nanomedicine. He authored of more than 145 journal papers in peer reviewed journals including several book chapters and 3 patents. His work have received more than 3000 citations and his h factor actualy is 31.

Abstract:

A series of Au nanoparticles functionalised with high coverage of TEMPO-modified disulfide have been prepared and studied by EPR, UV-Vis, TEM microscopy, Energy Dispersive X-ray analysis (EDX) and Thermogravimetric Analysis (TGA). In order to increase the coverage of spin labels on the particle surface, heat-induced size evolution and ligand exchange reactions were used. A one-pot reaction at room temperature led to gold nanoparticles with a controlled large size (ca. 7 nm) and high coverage of radicals. These nanoparticles showed a |Δms| = 2 transition at half-field which gives direct evidence of the presence of a high-spin state and allows an EPR study of the nature of the magnetic coupling between the spins. The results showed dominant antiferromagnetic interactions between radicals but at lower temperatures a ferromagnetic contribution was observed. The same diradical has been studied in solution, crystal and anchored to Au (111) flat surface showing anisotropic magnetic properties. We have also synthesized gold nanoparticles functionalized with high coverage of nitronyl nitroxide radical that preserve the same thermally modulated spin exchange radical interaction observed for the diradical in solution. This result has significant importance for developing functional hybrid surfaces and opens the possibility to be used as a new class of spin markers.

Biography:

Yo Tanaka received his PhD degree from the University of Tokyo. He worked as an Assistant Professor in the Department of Applied Chemistry, School of Engineering, University of Tokyo, and has been working as a Unit Leader in the Quantitative Biology Center, RIKEN, Japan, since 2011.

Abstract:

A microchip (also called as micro fluidic chip or micro chemical chip) is a palm sized small board with micro and nano fluidic channels fabricated by micro or nano machining techniques. It is widely utilized for the integration of complicated chemical and biochemical experimental processes. This is a spin-off technology from integrated circuit fabrication techniques in the field of electronics and information technology. Currently, it is applied to various wet processes in chemistry and biology and a number of sophisticated systems have been developed till now. There are several advantages including, saving the amount of chemical reagents and short analysis time. By exploiting these significant advantages, various kinds of chemical systems such as analysis, synthesis and cellular experiments have been integrated onto a microchip. Regarding this microchip technology, the author has developed several original technologies on fabrication, fluid control and construction of mechanical devices for bio-analysis. For example, totally glass based micro valves, pumps, filters and ultra-thin, flexible glass microchips as shown in Figure 1 have been demonstrated based on an
ultra-thin glass sheet handling techniques. In this work, these achievements are comprehensively introduced.

Biography:

Marta Lara-Lledó is an Agricultural Engineer specialized in Food Industries from Polytechnic University of Valencia (UPV). She has a Master’s and a PhD in Food Science and Engineering (UPV) and a Diploma in Packaging from Instituto Tecnológico del Embalaje, Transporte y Logística (ITENE). Since 2007, she is Technical
and Project Manager of New Materials and Packaging Systems department at ITENE. Nowadays, She is responsible for the Food Safety Area. She is working on several R&D projects specifically related to food packaging. She is specialized in the development, characterization and authorization of new packaging materials,
including the implementation of food contact materials legislation and verification processes for the proper performance and good manufacturing practices of the packaging materials.

Abstract:

Nanoparticles can be used in food contact materials to improve barrier, mechanical and thermal properties of biodegradable materials. The use of nanoparticles also allows the development of lightweight non-renewable polymers, maintaining their barrier, mechanical and thermal properties with less thickness. The use of nanoparticles is also possible for the development of active and intelligent materials with improved properties. Focusing on the improvement of biodegradable polymers properties, the formulation of organoclays and their incorporation into a PLA matrix allowed an increase of its barrier properties (↓ 25% OTR, ↓ 21% WVTR), mechanical properties (↑ 40-45% compression resistance) and an improvement of thermal properties. The reinforcement of barrier and mechanical properties of a PLA matrix was also using nanocelluloses extracted from different plants by-products (flax, hemp, oat, etc.). According to the plastic European Regulation for food contact materials (EU) Nº 10/2011, chemical and physical properties of nanoparticles could differ from those at large scale, leading to different toxicological properties. Therefore, case-by-case, risk assessment should be performed, and they can only be used if explicitly authorized and mentioned in Annex 1 of the plastic regulation. In the recent years, a notable increase in the number of authorized nanoparticles for food contact applications has been noticed in Europe, but harmonized measurement methods must be still developed to obtain consistent results over time and between laboratories. For the authorization of nanoparticles in US, a safety assessment should be also performed through a Food Contact Notification Program or alternative programs such as Threshold of Regulation (TOR) exemptions. The authorization procedures should be considered for the commercialization of these materials for food contact applications.

Biography:

Krishnamurthy G has completed his MPhil and PhD from Bangalore University after his Master’s in the same University. He is having a total of 16 years of teaching experience. During his tenure as Sir C V Raman Post-doctoral Fellow (2013-2014), he visited Lawrence Berkely National Laboratory, Berkely, CA, US. His research interests lie in nano/energy materials, electrochemisty, bio-medical materials, etc. He has published 28 papers in reputed journals and guided PhD students. He is a reviewer of several reputed international journals.

Abstract:

The efficient and cost effective electrocatalysts are of great interest for energy application due to the high cost and other associated problems of the existing ones. Here, in this work, the preparation of efficient electrocatalyst/substrate system by electroless deposition of non-noble metal nanoparticles, in particular the Ni/Multiwalled Carbon nanotubes(MWCNTs) has been prepared and tested for Methanol and Ethanol oxidation. The MWCNTs were synthesized by solvotehrmal procedure at a low temperature range of about 180–220°C in an autoclave system. The products were characterized by high-resolution transmission electron microscopy, powder X-ray diffraction, energy dispersive X-ray analysis and X-ray photoelectron spectroscopy. The Nickel nanoparticles with a size range of 5-10 nm were distributed almost uniformly on the surface of MWCNTs. The Ni/MWCNTs electrode has exhibited
remarkably higher current density of 145 mA/cm2 and a lower onset potential of -0.3 V in 0.1M CH3OH with 0.1 M H2SO4. The calculated average active surface area of MWCNTs and Ni/ MWCNTs’ electrode are 0.45 x 10-3 cm2 and 0.51 x 10-3 cm2 respectively and the surface coverage of Ni/MWCNTs’ electrode was 2.4409×10-7 mol/cm2. A significant electrocatalytic activity of Ni/MWCNTs for the oxidation of methanol and ethanol in acidic medium has been observed, which could be a positive result to be harnessed as a non-noble electrocatalyst/electrode system to improve the efficiency of the direct alcohol fuel cells.

Biography:

Heba ElSayed ElZorkany received her BSc in Biotechnology from Benha University in 2006. She joined the National Institution of Laser Enhanced Science, Cairo University as a Post-graduate student and she awarded a Diploma degree in Laser Applications in Biotechnology and Photobiology in 2008. She completed her MSc degree in 2013 (The photothermal effect of metallic nanoparticles on bacteria). She has enrolled in the PhD program at NILES, since 2014 to conduct her thesis titled “Efficiency of biocompatible quantum dot for cellular imaging using confocal laser scanning microscope”. She has been appointed as a Researcher at Nanotechnology and Advanced Materials Central Lab. (NAMCL), Agriculture Research Center (ARC) since 2010. Her research experiences include biotechnology, microbiology, photobiology, laser applications in biology, nanotechnology, spectroscopy, and microscopy. She is Confocal Laser Scanning Microscope (CLSM) & Cell Culture Specialist. She has participated in several international conferences.

Abstract:

Owing to its intrinsic photophysical properties quantum dots (QDs) act as a new tool for imaging and drug delivery. In this study, biocompatible silica-coated QDs were synthesized in order to track their cellular uptake in cancer cells. Firstly, Trioctylphosphine oxide capped CdSe QDs were synthesized by organometallic routes and ZnS shell were grown on them by injection solution of diethylzinc (Zn (Et)2) and hexamethyldislathiane ((TMS)2S) as Zn and S precursors. CdSe/ZnS QDs were then rendered water soluble by over-coating with silica using 3-Aminopropyltriethoxysilane (APTS) as silica precursor. The toxicological effects of silica-coated
CdSe/ZnS (Si-QDs) were investigated by exposing hep-G2 cells to different concentrations of Si-QDs then the mitochondrial activity was evaluated using WST-1 kit. The intracellular localization of Si-QDs in hep-G2 cells was investigated by Confocal Laser Scanning Microscopy (CLSM) equipped with CO2 incubator up to six hours. All stages of QDs formation were characterized by UV-Vis absorption, emission spectroscopy TEM, XRD, DLS and ζ-potential. Results showed that, high fluorescence QDs were synthesized with a size between 2 and 4 nm. Also, Silica coating process yielded final particle sizes of 6-18 nm which possessed strong luminescence
property. The cytotoxicity test results showed that Si-QDs were nontoxic even at higher concentrations as cells remained viable when exposed to Si-QDs at the highest concentration of 100 nM. The fluorescence imaging of hep-G2 cells exposed to Si-QDs by CLSM time lapse mode for 6 hours depicted the fast internalization of Si-QDs into the cells producing good fluorescence in the cytoplasmic portion. These results confirmed the effective role of these fluorescent materials in biological labeling and imaging applications.

Biography:

Francesca Costanzo has completed her PhD research at the University of Bologna, in 2000 with a thesis entitled: “Modified electrodes by conducting polymers”. Since her PhD, she combined her experimental experience with the theoretical work at different levels of approximation in the fields of solid state physics and condensed matter. Her competence in ab initio MD simulation allowed her to model, for example, the interaction of molecules on carbon materials (graphene, single and double walled nanotubes, fullerenes), and water splitting chemistry on transition metal oxide surfaces. She acquired her computational knowledge working at prestigious universities and institutions in Cambridge, Leiden, Padua and Barcelona. Her output includes 30 scientific articles, many invited talks and oral presentations.

Abstract:

Ionic liquids are one of the preferred options used by the industry for the storage of thermal energy in solar energy plants. Improving their thermophysical properties is an important goal to achieve more efficient heat storage and transportation media. A promising approach for improving these properties is to introduce nanoparticles dispersed in the ionic liquid or the molten salt, the so-called nanofluids. However, how thermophysical properties such as the heat capacity, self-diffusion, or heat conductivity depend on the microstructure of the nanofluids is still rather unknown. Molecular simulation, therefore, can play a major role in this research, as producing reliable experimental data for these systems is difficult and expensive. We have calculated by classical molecular dynamic simulations, thermal properties of disk-like graphene nanoflakes dispersed in organic solvent. In my contribution, I will discuss how the heat capacity and the thermal conductivity depend on the shape, the size and the density of the dispersed carbon nanoflakes. While thermal conductivity is well simulated by our classical model, the insertion of quantum corrections (QM) is necessary to calculate the heat capacity in good agreement with experiments. With our classical model including QM corrections, we are able
to shed light and gather basic understanding on the dependence of thermal transport properties on the nature of solute-solute and solute-solvent interaction.

Biography:

Romana Shahzadi is currently pursuing her PhD from University of Punjab, Lahore. She worked as Research Associate (2014-2016) at Centre for Environmental Protection Studies, Pakistan Council of Scientific and Industrial Research Labs, Lahore. She has completed her MPhil in Plant Genomics and Biotechnology from Agriculture University of Peshawar.

Abstract:

The metallic nanoparticles synthesis includes top-down and bottom-up method by means of chemical, physical and biological approach. The biosynthesis of silver nanoparticles is classified under bottom-up approach. Silver nanoparticles have the distinctive characteristics of anticancer, antimicrobial, catalytic and larvicidal activities. The Bacillus thuringiensis israelensis (Bti) have larvicidal activities against mosquitoes. So, the bacterial spore mixture is used for biosynthesis of silver nanoparticles. Nano particles were characterized using UV-Vis absorption spectroscopy for the confirmation of nano particles. XRD and SEM were used for the analysis of size and structure. The particle sizes were measured through SEM imaging ranging from 40 to 144.9 nm. The Bt-Ag NPs have mixed cubic and hexagonal structures. Interestingly, the mortality induced by Bt-AgNPs was comparatively high than that of the control against third instar larvae of A. aegypti (LC50 0.01 ppm and LC90 0.5 ppm) in all the tested concentrations, viz. 0.01, 0.05, 0.1, 0.5, and 1 ppm. Hence, the Bti-AgNPs nanoparticles would be significantly used as larvicidal against dengue vector mosquitoes Aedes aegypti.

Biography:

Peng-Sheng Wei received his PhD in Mechanical Engineering Department at University of California, Davis, in 1984. He has been a Professor in the Department of Mechanical and Electro-Mechanical Engineering of National Sun Yat-Sen University, Kaohsiung, Taiwan, since 1989. He has contributed to advancing the
understanding of and to the applications of electron and laser beam, plasma, and resistance welding through theoretical analyses coupled with verification experiments. Investigations also include studies of their thermal and fluid flow processes, and formations of the defects such as humping, rippling, spiking and porosity. He has published more than 80 journal papers, given keynote or invited speeches in international conferences more than 90 times. He is a Fellow of AWS (2007), and a Fellow of ASME (2000). He also received the Outstanding Research Achievement Awards from both National Science Council (2004), and NSYSU
(1991, 2001 and 2004), the Outstanding Scholar Research Project Winner Award from National Science Council (2008), the Adams Memorial Membership Award from AWS (2008), the Warren F Savage Memorial Award from AWS (2012), and the William Irrgang Memorial Award from AWS (2014). He has been the Xi- Wan Chair Professor of NSYSU since 2009, and Invited Distinguished Professor in the Beijing University of Technology, China, during 2015-2017.

Abstract:

Pore formation and its shape in solid influence not only microstructure of materials, but also contemporary issues of various sciences of biology, engineering, foods, geophysics and climate change, etc. In order to remove and control porosity, understanding its formation is important. A pore formed in solid is a consequence of a bubble nucleated by super-saturation and entrapped by a solidification front. This work accounts for realistic mass and momentum transport across a self-consistently and analytically determined shape of the bubble cap, whose surface is in physico-chemical equilibrium beyond the solidification front. Accurate determination of contact angle from a realistic shape of the cap is required to predict the relevant shape of the pore in solid. It was systematically found that there are two different solute transport models subject to thin and thick thicknesses of concentration boundary layers on the solidification front. Case 1 accounts for species transport from the pore across an emerged cap through a thin concentration boundary layer on the solidification front into surrounding liquid in the early stage, whereas Case 2 is subject to species transport from the surrounding liquid across a submerged cap within a thick concentration boundary layer into the pore. The results find increases in interfacial properties such as Henry’s law constant and Bond number decrease the pore radius. The predicted pore shape agrees with experimental data. A realistic prediction and control of the growth of the pore shape has therefore been obtained.

Biography:

Wilson Engelmann has obtained his PhD in Law/Unisinos (Brazil) and a Professor and Researcher of the Post-Graduate Program in Law, Master and Doctorate and Executive Coordinator of the Professional Master’s in Corporate Law and Business Law both at University of the Sinos Valley – Unisinos, Brazil. He is the Leader of JUSNANO Research Group and a scholarship holder of Research Productivity CNPq/Brazil. He is developing a research project, since 2008, on regulatory issues related to nanotechnologies and analysis of their social and ethical impacts.

Abstract:

Statement of the Problem: The use of nanoscale is currently growing: in research, industrial production and in the consumer market. There is no state legislative regulation on the matter. There is the rise of self-regulation, as well as the creation of norms by other social actors. The system of Law needs to enter in the context of innovation, granting legal effects to this regulatory production. The temporality of the new forms of regulation and the ability to deal with future risks and damages represent other challenges for the legal area.

Purpose of this study: It is based on the 79 documents of the OECD "Series on the Safety of Manufactured Nanomaterials", is to analyze the perception of risks and the way that the juridicization of the unknown future damages that might be generated from the manipulation of the nanoscale, especially in relation to human health and the preservation of the environment.

Methodology & Theoretical Orientation: the functionalist method will be used in a systemic-constructivist perspective, risk theory (Luhmann) and content analysis (Bardin). Comprehensive keywords were used to enable data collection in the 79 documents, which
are: "risk", "environmental safety" or "environment", "human health" and "manufactured nanomaterial".

Findings: The word "manufactured nano-material" has 4,934 repetitions; "Risk" has 4,214 repetitions; "Environment" has 2,204 repetitions and "human health" has 1,478 repetitions. This shows extreme concern about the risks which nanomaterials could pose to the environment and human health.

Conclusion & Significance: the observed keywords show that manufactured nano-materials may generate risks for the environment and human health, with little concern for the environmental safety, which has only 48 repetitions. For this reason it is important to
structure the framework as a legal risk management tool for nanotechnology companies to gather information and deal with future and uncertain damages. In this scenario is relevant an adequate evaluation of the ethical-social impacts in the structuring of selfregulation.