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Alessandro Falconier


Alessandro Falconier

University of Pisa, Italy

Biography

Alessandro Falconieri has his expertise in the field of molecular biology, nanotechnologies and neuro-mechanobiology. His study of axonal growth following mechanical stimulation proposes a new model of neuritic development based on the establishment of a complex dialogue between local phenomena (i.e. axonal transport and local translation). The model based on this "cross-talk" came from his PhD work which ended in June 2021. In the recent period, he is investigating the molecular pathways activated by tension (with particular focus on signal transduction) as well as the mechanisms of repair and recovery following prolonged stimulation. The prospect of exploiting mechanical stimulation to accelerate the rate of axonal outgrowth is very intriguing as it would give the possibility of proposing a new therapeutic target for the treatment of neurons damaged following injury or disease.

 

Abstract

Abstract : Magnetically-actuated nanoparticles: A novel method to unravel the molecular mechanisms evoked by mechanical tension